Profile
I am a Computer Scientist specialising in Computational Biology and Neuro-Oncology, acting as a strategic bridge between advanced algorithmic development and clinical discovery. With a PhD in Computer Science and over 7 years of industry project management experience, I excel in transforming complex, high-dimensional spatial omics data (e.g., 10X Visium HD, GeoMx) into interpretable, interactive digital assets. My work focuses on uncovering immune mechanisms in Glioblastoma (GBM) through bespoke clustering algorithms and deploying “living results” via web-based platforms to drive both scientific insight and public fundraising impact.
Experience
- Algorithmic Leadership: Developed a novel clustering algorithm utilising the Dirichlet Process to automatically determine optimal niches in spatial transcriptomic data.
- GBM Spatial Analysis: Lead analyst for GBM tissue cohorts in the Department of Surgery and Cancer, utilising 10X Visium HD and GeoMx to deliver mechanistic insights into immune evasion.
- Stakeholder Delivery: Designed and deployed public-facing interactive web applications (HTML/Shiny) to visualise results for clinical collaborators and lab fundraisers.
- Advanced Inference: Performed cell-type deconvolution and transcription activity mapping to identify novel therapeutic targets in the GBM microenvironment.
- Reproducibility: Established and maintained robust, containerised (Docker/Nextflow) bioinformatic workflows for high-plex spatial data.
Technologies Used: Python, R, Shiny, Docker, Nextflow
Developed Graph Neural Network (GNN) models with attention mechanisms for Drug-Target Interaction prediction.
Technologies Used: Python (PyTorch)
- Fine-tuned NLP (BERT) models for security applications and built RESTful APIs.
- Visualised complex network data using node-link diagrams for Twitter news analysis.
- Developed Web UIs and database management for cryptocurrency trend prediction platforms.
Technologies Used: Python, Javascript, HTML5, MongoDB, R
- Led large-scale IT deployments for government, schools, and hospitals.
- Managed end-to-end project lifecycles, including budgets, tracking, and multi-disciplinary coordination.
- Developed instructional materials and led staff training sessions on new software systems.
- Managed IT infrastructure projects and coordinated between technical teams and public stakeholders.
Interior designing using 3DsMax, SketchUp, and AutoCAD.
Full-stack web development primarily using PHP.
- Managed developmental models and production plans.
- Analysed circuit defects and provided technical advice for model modifications.